ANALYSIS OF PETROLEUM POLLUTION ON SERUM TRACE ELEMENT LEVEL, OXIDATIVE STATUS, AND BIOCHEMICAL INDICES IN THE RESIDENTS OF AN OIL HOST COMMUNITY (UGBEGUNGUN) IN DELTA STATE, NIGERIA
- Project Research
- 1-5 Chapters
- Abstract : Available
- Table of Content: Available
- Reference Style: APA
- Recommended for : Student Researchers
- NGN 3000
ABSTRACT
Activities of crude oil refining disrupt natural ecosystems which expose residents to environmental pollution, and consequently pose threat to their health and wellness. This study was aimed to analyze serum trace elements levels, oxidative status, and biochemical indices in the residents of an oil host community (Ugbegungun) in Delta State, Nigeria. A total of 100 subjects were recruited for this study which comprised 50 individuals from Ugbegungun and 50 individuals from Okada, a non-oil host community. Serum levels of lead (Pb), zinc (Zn), and cadmium (Cd) were evaluated using Atomic Absorption Spectrophotometer. Alanine transaminase (ALT), aspartate transaminase (AST) and alkaline phosphate (ALP) activities, and urea and creatinine were all evaluated with a commercially available enzymatic kit. The oxidative and antioxidative activities in the serum were estimated using the semi-automated spectrophotometric procedure. Enzyme-linked immunoassay was used to assess tumor necrotic factor-alpha (TNF-α) and 8-hydroxy-2-deoxyguanosine (8-OHdG). The results showed that serum levels of Pb, Cd, urea, creatinine, ALT, AST, ALP, malondialdehyde, TNF-α, and 8- OHdG were significantly higher (p<0.05) in female and male residents of Ugbegungun when compared with the female and male residents of the non-oil host community. The activities of superoxide dismutase, catalase, glutathione reductase, and total antioxidant capacity were significantly lower (p<0.05) in both female and male residents of Ugbegungun when compared with the residents of non-oil host community. In conclusion, the residents of an oil host community in Nigeria may be at high risk of kidney and liver toxicity through oxidative stress induction associated probably with heavy metal accumulation in the system.
Related Project Materials
TRANSNATIONAL CRIME MANAGEMENT IN ECOWAS SUB-REGION: A CASE OF NIGERIA AND NIGER REPUBLIC
ABSTRACT
Crimes and criminality are counterproductive to every human society, ironically, its occurrence is universal. To a large extent,...
THE ROLE OF MEDIATION IN THE RUSSIAN- UKRAINE CONFLICT
ABSTRACT
This study was carried out to examine the role of mediation in the Russian- Ukraine ...
WOMEN EMPOWERMENTAND COMMUNITY DEVELOPMENT A STUDY OF BWARI LOCAL GOVERNMENT AREA, F.C.T, NIGERIA
ABSTRACT
Women empowerment is all encompassing, so this work will want to narrow it to the subject of women development and the impact of...
EXPERIENCE AND PERCEIVED MEANS OF PREVENTION OF SEXUAL ABUSE AMONG FEMALE ADOLESCENT HAWKERS IN MARKETS IN IBADAN NORTH EAST LOCAL GOVERNMENT AREA, IBADAN, NIGERIA
ABSTRACT
Involvement of a child or adolescent in a sexual activity is a major cause of reproductive health problem among female children...
ANALYSIS OF THE LAW ON COMPANY MEETINGS IN CONTEMPORARY CORPORATE GOVERNANCE IN NIGERIA
ABSTRACT
This study analyzed the Law on Company Meeting in Modern Day Corporate Governance in Nigeria. It principally discussed the conce...
EFFECT OF PARTNERSHIP AND JOINT VENTURE BUSINESS IN SMALL SCALE BUSINESS IN NIGERIA, PROBLEM AND PROSPECT
ABSTRACT
Formation of joint ventures between SMEs is one of the recent efforts in improving SME growth in Nigeria and ad...
AN ASSESSMENT OF READING CULTURE OF PRIMARY SCHOOL PUPILS AND THEIR ACADEMIC PERFORMANCE IN ENGLISH LANGUAGE
BACKGROUND OF THE STUDY
There is no question that a country's degree of development is directly rel...
THE IMPACT OF CHANGE MANAGEMENT ON PROJECT SUCCESS
Abstract: This study investigates the impact of change management on project success, aiming to: 1) identify...
ATTITUDES OF UNDERGRADUATES OF SOCIAL STUDIES UNIT TOWARDS ENTREPRENEURSHIP
Abstract
This study x-rayed the attitudes of undergraduates of Social Studies Unit towards entrepreneur...
THE INFLUENCE OF FINANCIAL ACCOUNTING REPORTING ON THE MANAGEMENT OF A BUSINESS ORGANIZATION
Abstract
This study sought to assess the influence of financial accounting reporting on the management...
